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三七根茎的化学成分研究
引用本文:曾江,崔秀明,周家明,江志勇,张雪梅,陈纪军. 三七根茎的化学成分研究[J]. 中药材, 2007, 30(11): 1388-1391
作者姓名:曾江  崔秀明  周家明  江志勇  张雪梅  陈纪军
作者单位:1. 文山三七研究院药物研究所,云南文山,663000;文山三七科技创新中心,云南文山,663000
2. 中国科学院昆明植物研究所,云南昆明,650204
基金项目:云南省农社攻关重点项目
摘    要:目的:研究五加科人参属植物三七Panaxnotoginseng(Burk)F.H.Chen根茎中的化学成分。方法:利用大孔吸附树脂柱、硅胶柱、RP-8和RP-18柱进行化合物的分离纯化,根据其理化性质和光谱数据进行结构鉴定。结果:从三七根茎中分离得到8个化合物,分别鉴定为:人参皂苷Rh4(ginsenoside Rh4,Ⅰ),人参皂苷Rh1(ginsenosideRh1,Ⅱ),人参皂苷Re(ginsenoside Re,Ⅲ),三七皂苷R1(notoginsenoside R1,Ⅳ),人参皂苷Rd(ginsenoside Rd,Ⅴ),人参皂苷Rb1(ginsenoside Rb1,Ⅵ),三七皂苷S(notoginsenoside S,Ⅶ),三七皂苷T(notoginsenoside T,Ⅷ)。结论:化合物Ⅰ为首次从该植物中分离得到,化合物Ⅶ和Ⅷ为首次从三七根茎中分离得到。

关 键 词:三七根茎  化学成分  三萜皂苷
文章编号:1001-4454(2007)11-1388-04
修稿时间:2007-05-08

Studies on Chemical Constituents from Rhizomes of Panax notoginseng
ZENG Jiang,CUI Xiu-ming,ZHOU Jia-ming,JIANG Zhi-yong,ZHANG Xue-mei,CHEN Ji-jun. Studies on Chemical Constituents from Rhizomes of Panax notoginseng[J]. Journal of Chinese medicinal materials, 2007, 30(11): 1388-1391
Authors:ZENG Jiang  CUI Xiu-ming  ZHOU Jia-ming  JIANG Zhi-yong  ZHANG Xue-mei  CHEN Ji-jun
Affiliation:Wenshan Institute of Sanqi Research, Institute of Medicine Research, Wenshan 663000, China.
Abstract:OBJECTIVE: To study the chemical constituents from rhizomes of Panax notoginseng. METHODS: The constituents were isolated and purified by various chromatogragraphic methods, all compounds were identified on the basis of special analysis and physicochemical characters. RESULTS: Eight compounds were isolated from the 80% alcohol extract of the rhizomes and their structures were identified as ginsenoside Rh4 (I), ginsenoside Rh1 (II), ginsenoside Re (III), notoginsenoside R1 (IV) , ginsenoside Rd (V), ginsenoside Rh1 (VI), notoginsenoside S (VII), notoginsenoside T (VIII). CONCLUSION: Compound I was isolated from this plant for the first time, Compound VII, VIII are isolated from rhizomes of Panax notoginseng for the first time.
Keywords:Rhizomes of Panax notoginseng  Chemical constituents  Triterpene saponin
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