异丙酚对全麻术后病人恶心、呕吐的影响

目的 观察异丙酞预防术后恶心、呕吐的作用。方法 47例拟行选择性腹腔镜胆囊切除术病人被随机分为A组(24例)和B组(23例)。A组以芬太尼、异丙酞和万可松行麻醉诱导；B组以芬太尼、硫喷妥钠和万可松诱导。两组均以吸入异氟醚维持。观察两组病人的麻醉恢复特点和术后24h内恶心、呕吐发生率及应用镇吐药病人数。结果 两组病人术后唤醒时间、完全清醒时间及术后恶心、呕吐的发生率及应用镇吐药病人数相比较，A组各值均明显低于B组(P＜0．05)。结论 异丙酞行全身麻醉可有效地预防术后恶心、呕吐，并可显著缩短麻醉恢复时间。

Effect of propofol on postoperative nausea and vomiting in the patients undergoing general anesthesia

Objective To observe the effect of propofol in preventing postoperative nausea and vomiting.Methods Forty-seven patients scheduled for select laparoscopy cholecystectomy were randomly divided into group A(24 cases) and group B(23 cases).Group A received fentanyl,propofol and vecuronium for induction of anesthesia,group B were induced with fentanyl,thiopental and vecuronium.Anesthesia was maintained by isoflurane inhalation in two groups.Recovery characteristic,the incidence of postoperative nausea and vomiting,and the patient number of antiemetic use were observed for 24h.Results Postoperative awakening time,postoperative awake time,the incidence of postoperative nausea and vomiting,and the patient number of antiemetic use in group A were much lower than those in group B(P<0.05).Conclusion Propofol administered for general anesthesia is effective in preventing postoperative nausea and vomiting,and can shorten the time of anesthetic recovery markedly.