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血清抗角蛋白自身抗体滴度消长对皮肤烫伤的影响
引用本文:刘玉峰 刘彦仿. 血清抗角蛋白自身抗体滴度消长对皮肤烫伤的影响[J]. 中国皮肤性病学杂志, 1992, 6(2): 67-68
作者姓名:刘玉峰 刘彦仿
作者单位:第四军医大学西京医院皮肤科,第四军医大学西京医院病理解剖教研室,第四军医大学西京医院病理解剖教研室,第四军医大学西京医院皮肤科,第四军医大学西京医院皮肤科,第四军医大学西京医院皮肤科,第四军医大学西京医院皮肤科 710032,710032,710032,710032,710032
摘    要:
作者对家兔血清抗角蛋白自身抗体(AK auto Ab)滴度低下(实验组)及滴度正常(对照组)的皮肤烫伤进行了对比观察,并对烫伤后分界性炎症、表皮修复、表皮角朊细胞胞浆AK auto Ab含量进行检测。结果显示,实验组损伤明显、结痂较晚,分界性炎症出现较迟、程度较轻,表皮修复迟缓、愈合较慢,而角朊细胞胞浆内IgG AK auto Ab含量较低。提示,正常滴度的血清AK auto Ab在皮肤烫伤发展及修复的过程中,可能对机体起着重要的保护作用。

关 键 词:角蛋白,自身抗体  烫伤

Effect of AK auto Ab on scalded skin
Liu Yufeng,Liu Yan fang,Ding Huaye,et al.. Effect of AK auto Ab on scalded skin[J]. The Chinese Journal of Dermatovenereology, 1992, 6(2): 67-68
Authors:Liu Yufeng  Liu Yan fang  Ding Huaye  et al.
Affiliation:Liu Yufeng,Liu Yan fang,Ding Huaye,et al. Department of Dermatolology,Xijing Hospital. Fourth Military Medical University,Xian
Abstract:
The distribution of inflammatory cells and the content of AK auto Abin epidermic keratinocytoplasma in scalded skin of rabbits, were observed under microscope and MSPM. The level of AK auto Ab in sera was normal (normal group), or lower (lower group). It was found that the inflammation was much more obvious and the content of AK auto Ab in keratinocytoplasma was higher in the normal group than that in lower group. The results suggested that AK auto Ab may have an protective effect in the development of the skin damage caused by scalding.
Keywords:Keratin autoantibodies Scald
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