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茵陈蒿汤加减治疗ABO血型不合50例
引用本文:姜英凤,石祥奎.茵陈蒿汤加减治疗ABO血型不合50例[J].河南中医,2016(5):869-871.
作者姓名:姜英凤  石祥奎
作者单位:徐州市妇幼保健院,江苏徐州,221009
基金项目:江苏省徐州市临床药学课题(编号:XZZDYI401)
摘    要:目的:观察茵陈蒿汤加减治疗ABO血型不合的临床疗效。方法:100例妊娠24周以后测定的Ig G抗A(B)抗体效价结果中比值≥1:128的孕妇,随机分为对照组和研究组,每组各50例。对照组予维生素C、维生素E口服;研究组口服茵陈蒿汤加减方。观察两组患者的临床疗效。结果:研究组有效率为70.0%,对照组有效率为58.0%,两组有效率比较,差异有统计学意义(P0.05)。在新生儿病理性黄疸的发生率方面,研究组病理性黄疸发生率为8.0%,对照组病理性黄疸发生率为14.0%,两组病理性黄疸发生率比较,差异具有显著性意义(P0.05)。两组均未发现新生儿溶血。结论:茵陈蒿汤加减治疗ABO血型不合临床疗效显著,且能有效预防新生儿ABO血型不合引起的黄疸。

关 键 词:ABO血型不合  茵陈蒿汤  抗体效价

Fifty Cases with ABO Blood Group Incomaptibility Treated with Modified Virgate Wormwood Decoction
Abstract:Objective:To observe the clinical effects of Modified Virgate Wormwood Decoction on ABO blood group incompatibility.Methods:Totally 100 pregnant women 24 weeks after pregnancy with ratio≥ 1:128 of valence of antibody of IgG anti-A (B) were randomly divided into control group and research group,with 50 cases in each group.Control group were given Vitamin C and Vitamin E for oral administration while research group were orally given Modified Virgate Wormwood Decoction.The clinical effects of the two groups were observed.Results:The effective rate was 70.0% in research group and 58.0% in control group;the difference between the two groups had statistical significance (P < 0.05).For the neonatal pathologic jaundice,the occurrence rate was 8.0% in research group and 14.0% in control group,with statistical significance (P < 0.05).No neonatal hemolysis was discovered in any group.Conclusion:Modified Virgate Wormwood Decoction has remarkable therapeutic effects on ABO blood group incompatibility and it can effectively prevent the jaundice due to ABO blood group incompatibility.
Keywords:ABO blood group incompatibility  Virgate Wormwood Decoction  valence of antibody
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