A population model of prostate cancer incidence |
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Authors: | Tsodikov A Szabo A Wegelin J |
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Affiliation: | Department of Public Health Sciences, Division of Biostatistics, University of California Davis, One Shields Avenue, Davis, CA 95616, USA. atsodikov@ucdavis.edu |
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Abstract: | Introduction of screening for prostate cancer using the prostate-specific antigen (PSA) marker of the disease led to remarkable dynamics of the incidence of the disease observed in the last two decades. A statistical model is used to provide a link between dissemination of PSA and the observed transient population responses. The model is used to estimate lead time, overdiagnosis and other relevant characteristics of prostate cancer screening. |
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Keywords: | screening mixture models prostate cancer |
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