阿托品滴眼液与托品酰胺滴眼液预防青少年近视眼效果的比较

目的：比较0.05%阿托品滴眼液与0.25%托品酰胺滴眼液预防青少年近视眼效果。方法：对近视可能者158人（302眼）随机分为三组：阿托品组：每晚睡前点用0.05%阿托品滴眼液;托品酰胺组：每晚睡前点用0.25%托品酰胺滴眼液;对照组：每晚睡前点用0.05%呋喃西林滴眼液。定期复查视力、屈光状态、眼轴。结果：①近视眼患病率：两治疗组的患病率均小于对照组,同时阿托品组的患病率较托品酰胺组更少;②用药前后眼轴的变化：阿托品组没有明显的变化,托品酰胺组和对照组均有显著的延长;③畏光症状：用药初期两治疗组均有不同程度的症状,用药2月后症状基本消失。结论：近视可能者坚持每天应用0.05%阿托品滴眼液可以预防近视眼的发生。

To compare the effects of preventing myopia by using atropine eyedrop and tropicamide eyedrop in callan

Objective:To compare the effects of preventing myopia by using 0.05% atropine eyedrop and 0.25% tropicamide eyedrop in callan.Methods:158 possible myopia callan(302 eyes) were divided into 3 groups by freedom: atropine group: 0.05% atropine eyedrop was used in every-evening;tropicamide group: 0.25% tropicamide eyedrop was used in every-evening;control group: 0.05% furacilinum eyedrop was used in every-evening.The visual acuity,the estate of refraction and the axial length were examined on time.Results:(1) Morbidity rate of myopia.The two treatment groups were both lower than control group;the atropine group was lower than the tropicamide group;(2) the changes of axial length before and after using eyedrop.There was no evident change in the atropine group;the axial length was obvious prolonged in tropicamide group and control group.(3) The phengophobia symptom.In the initial stages the two treatment groups had difference symptom;after 2 month later the symptom was mostly dismissed.Conclusions: It can prevent myopia by using 0.05% atropine eyedrop every-day in possible myopia callan.