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| 不同剂量维生 D干预治疗 案对婴幼儿血清25-羟维生素D水平的影响 | |
| 引用本文： | 张霞娟,鲍莉芳,鲍舟君,王英,李翊卫,王晔恺.不同剂量维生 D干预治疗 案对婴幼儿血清25-羟维生素D水平的影响[J].中国临床药理学与治疗学,2011,16(12):1419-1422. |
| 作者姓名： | 张霞娟 鲍莉芳 鲍舟君 王英 李翊卫 王晔恺 |
| 作者单位： | 1. 舟山市妇幼保健院儿保科,舟山316000,浙江 2. 舟山医院检验科,舟山316004,浙江 3. 舟山医院细胞分子生物学实验室,舟山316004,浙江 |
| 摘 要： | 目的:比较不同(剂量)维生素D干预治疗方案对血清25-羟维生素D水平的影响.方法:选取2011年3月至10月血清25-羟维生素D缺乏或相对缺乏的婴幼儿102例,分为以下用药方案:A组:一次性维生素D 15万IU；B组:一次性维生素D 20万IU；C组:一次性维生素D 30万IU；D组:每日维生素A 3600 IU+维生素D 2000IU,持续1个月.一个月后取清晨空腹血,电化学发光法检测其血清25-羟维生素D水平.结果:A、B、C、D组方案用药后血清25-羟维生素D水平均高于用药前(P＜0.01).A、B、C组血清25-羟维生素D提升水平均高于D组(P＜0.01)；C组血清25-羟维生素D提升水平高于A、B组(P＜0.01).结论:一次性维生素D 15～20万IU的是安全有效干预治疗方案. |
| 关 键 词： | 25-羟维生素D 维生素D缺乏儿童 电化学发光法 |
Dosage research of serum 25-hydroxyvitamin D levels on different intervention treatments for children |
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| ZHANG Xia-juan , BAO Li-fang , BAO Zhou-jun , WANG Yin , LI Yi-wei , WANG Ye-kai.Dosage research of serum 25-hydroxyvitamin D levels on different intervention treatments for children[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2011,16(12):1419-1422. | |
| Authors: | ZHANG Xia-juan BAO Li-fang BAO Zhou-jun WANG Yin LI Yi-wei WANG Ye-kai |
| Institution: | ZHANG Xia-juan1,BAO Li-fang 1,BAO Zhou-jun2,WANG Yin2,LI Yi-wei2,WANG Ye-kai 3 1 Child Health Department,the Maternal and Child Care Service Centre of Zhoushan,Zhoushan 316000,Zhejiang,China,2 Clinical Laboratory,Zhoushan Hospital,Zhoushan 316004,3 Molecular and Biology Laboratory |
| Abstract: | AIM: To explore the serum 25-hydroxyvitamin D levels effected by different intervention treatments.METHODS: 102 children with vitamin D deficiency were selected and divided as follows: Group A: VitD 150000 IU once;Group B: VitD 200000 IU once;Group C: VitD 300000 IU once;Group D: VitA 3600 IU+VitD 2000 IU per day,lasting for a month.A month later,their serum 25-hydroxyvitamin D levels were rechecked by electrochemistry method.RESULTS:The serum 25-hydroxyvitamin D levels after treated in Group A,B,C,D were s... |
| Keywords: | 25-hydroxyvitamin D Children with vitamin D deficiency Electrochemistry method |
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