Diffuse optical tomography using multi-directional sources and detectors |
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Authors: | Takeaki Shimokawa Toshihiro Ishii Yoichiro Takahashi Satoru Sugawara Masa-aki Sato Okito Yamashita |
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Affiliation: | 1ATR Neural Information Analysis Laboratories, Kyoto 619-0288, Japan;2Ricoh Institute of Future Technology, RICOH Company Ltd., Miyagi 981-1241, Japan;3Brain Functional Imaging Technologies Group, CiNet, Osaka 565-0871, Japan;4These authors contributed equally to this work |
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Abstract: | Diffuse optical tomography (DOT) is an advanced imaging method used to visualize the internal state of biological tissues as 3D images. However, current continuous-wave DOT requires high-density probe arrays for measurement (less than 15-mm interval) to gather enough information for 3D image reconstruction, which makes the experiment time-consuming. In this paper, we propose a novel DOT measurement system using multi-directional light sources and multi-directional photodetectors instead of high-density probe arrays. We evaluated this system’s multi-directional DOT through computer simulation and a phantom experiment. From the results, we achieved DOT with less than 5-mm localization error up to a 15-mm depth with low-density probe arrays (30-mm interval), indicating that the multi-directional measurement approach allows DOT without requiring high-density measurement.OCIS codes: (100.3010) Image reconstruction techniques, (110.0113) Imaging through turbid media, (170.3880) Medical and biological imaging |
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