| 植物雌激素与前列腺癌及良性前列腺增生 |
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| 引用本文： | 冯耀,夏欣一,黄宇烽.植物雌激素与前列腺癌及良性前列腺增生[J].中华男科学杂志,2007,13(5):457-461. |
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| 作者姓名： | 冯耀 夏欣一 黄宇烽 |
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| 作者单位： | 1. 南京军区南京总医院解放军临床检验医学研究所,江苏,南京,210002;南京师范大学生命科学学院,江苏,南京,210097
2. 南京军区南京总医院解放军临床检验医学研究所,江苏,南京,210002 |
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| 摘 要： | 植物雌激素是一类广泛分布于各类植物中的结构与雌激素相似并具有弱雌激素及抗雄激素活性的天然活性物质。PCa与BPH是雄激素依赖性及与年龄相关的疾病,近年来流行病学调查和实验研究均表明植物雌激素对PCa与BPH有防治作用。其机制可能与植物雌激素对性激素的调节、对细胞增生的抑制、诱导细胞凋亡及抗氧化作用等有关。
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| 关 键 词： | 植物雌激素 前列腺癌 良性前列腺增生 |
| 文章编号： | 1009-3591（2007）05-0457-05 |
| 收稿时间： | 2007-01-10 |
| 修稿时间： | 2007-01-102007-03-05 |
Effects of Phytoestrogens on Prostate Cancer and Benign Prostatic Hyperplasia |
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| FENG Yao,XIA Xin-yi,HUANG Yu-feng.Effects of Phytoestrogens on Prostate Cancer and Benign Prostatic Hyperplasia[J].National Journal of Andrology,2007,13(5):457-461. |
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| Authors: | FENG Yao XIA Xin-yi HUANG Yu-feng |
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| Institution: | 1. PLA Research Institute of Clinical Laboratory Medicine, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, 21002 Jiangsu, China ; 2. Institute of Life Science, Nanjing Normal Univeristy, Nanfing, Jiangsu 210097, China |
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| Abstract: | Phytoestrogens are non-steroidal estrogens widely distributed in many kinds of plants.They are natural compounds structurally similar to estrogen and with estrogenic or anti-androgenic activities.Prostate cancer(PCa)and benign prostatic hyperplasia(BPH)are androgen-dependent and associated with age.Recently,in many epidemiological and experimental researches,it has been reported that phytoestrogens play a role in the prevention and treatment of PCa and BPH.Regulation of sexual hormones,inhibition of cell proliferation,induction of cell apoptosis and anti-oxidation of such plant estrogens may be involved in the mechanisms. |
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| Keywords: | phytoestrogen prostate cancer benign prostatic hyperplasia |
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