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吉西他滨联合顺铂治疗复发性卵巢癌的临床研究
引用本文:焦鲁霞,白洁,温春燕,王雪英. 吉西他滨联合顺铂治疗复发性卵巢癌的临床研究[J]. 解放军保健医学杂志, 2009, 0(3): 212-214
作者姓名:焦鲁霞  白洁  温春燕  王雪英
作者单位:解放军总医院妇产科;新疆军区机关门诊部;
摘    要:
目的研究吉西他滨联合顺铂治疗复发性卵巢癌的疗效及毒性。方法对32例复发性卵巢癌患者应用吉西他滨1000mg/m^2,第1、8d静注,联合顺铂75mg/m^2,分为第1、2、3d静注,21d为1疗程。结果32例患者有效率为53.1%.其中完全有效7例(21.8%),部分有效10例(31.3%),无进展生存期平均为3.5个月,毒副反应主要为白细胞减少,但均为可逆性。结论吉西他滨加顺铂是治疗复发性卵巢癌的有效方案,其毒副反应均可耐受。

关 键 词:卵巢癌  肿瘤复发  化学疗法  吉西他滨:  顺铂

Gemcitabine plus cisplatin in treatment of recurrent ovarian cancer
JIAO Luxia,BAI Jie,WEN Chunyan. Gemcitabine plus cisplatin in treatment of recurrent ovarian cancer[J]. Journal Of Health Care And Medicine in Chinese Pla, 2009, 0(3): 212-214
Authors:JIAO Luxia  BAI Jie  WEN Chunyan
Affiliation:The department of Obstetrics and Gynecology;PLA General Hospital;Beijing 100853;China
Abstract:
Objective To evaluate the efficacy and toxicities of gemcitabine plus cisplatin for patients with relapsed ovarian cancer.Methods Thirty tow patients with recurrent ovarian carcinoma received gemcitabine(1000 mg/m2,d1,d8)plus cisplatin(75 mg/m2,d1-3)of each 21 day cycle.Results Of 32 patients,there were 7(21.8%)complete and 10(31.3%)partial responses,for an overall response rate of 53.1%.The leukopenia is the most important toxicity.Conclusions Cisplatin plus gemcitabine is effective in patients with relaps...
Keywords:Ovarian neoplasms  Neoplasm recurrence  Chemotherapy  Gemcitabine  Cisplatin  
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