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凝血功能四项、TF、AT-Ⅲ对原发性肝癌的诊断意义
引用本文:罗春华. 凝血功能四项、TF、AT-Ⅲ对原发性肝癌的诊断意义[J]. 社区医学杂志, 2011, 9(12): 3-4
作者姓名:罗春华
作者单位:衡阳县人民医院检验科,湖南,421200
摘    要:
目的对150例原发性肝癌(PHC)患者分别进行凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)、组织因子(TF)及抗凝血酶Ⅲ(AT-Ⅲ)活性6项指标进行检测和对比分析。方法分别测定PHC早期患者(72例)、PHC晚期患者(78例)的PT、APTT、TT及FIB、TF、AT-Ⅲ的活性,比较两组之间的差异。结果晚期原发性肝癌组的FIB、PT、APTT、TT、AT-Ⅲ与早期原发性肝癌患者比较差异有统计学意义(P<0.05);早期肝癌组、晚期肝癌组TF与对照组相比,差异均有统计学意义(P<0.05),但早期肝癌组与晚期肝癌组TF差异无统计学意义(P>0.05)。结论原发性肝癌患者凝血功能检测及TF、AT-Ⅲ活性变化在一定程度上能反映肝脏损害程度,对临床肝癌患者病情检测、预后判断及指导治疗有一定的应用价值。

关 键 词:原发性肝癌  凝血功能  组织因子  抗凝血酶

The value of coagulation parameters in paitents with parimary hepatic carcinoma
LUO Chun-hua. The value of coagulation parameters in paitents with parimary hepatic carcinoma[J]. journal of community medicine, 2011, 9(12): 3-4
Authors:LUO Chun-hua
Affiliation:LUO Chun-huaThe People's Hospital of Hengyang Town,hunan 421200,China
Abstract:
Objective To examine and compare the level of prothrombin time,activated partial throm bop last in time,fibrinogen,thrombin time in 150 patients with parmary hepatic carcinoma(PHC).Methods Patients with early PHC and advanced PHC were determined respectively with 72 cases and 78 cases of PT,APTT,TT,FIB,TF and AT-III,compare two groups of the level of difference Clotting time and activated level.Results The results show,the early PHC group significant decrease of FIB to compare with the advanced PHC group(P<...
Keywords:Parmary hepatic carcinoma  Coagulation parameters  TF  AT-Ⅲ
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