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A new mechanism preventing proarrhythmia in chronic heart failure: rapid phase-III repolarization explains the low proarrhythmic potential of amiodarone in contrast to sotalol in a model of pacing-induced heart failure |
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| Authors: | Frommeyer Gerrit Milberg Peter Witte Patricia Stypmann Jörg Koopmann Matthias Lücke Martin Osada Nani Breithardt Günter Fehr Michael Eckardt Lars |
| Affiliation: | 1. Department of Cardiology and Angiology, Hospital of the Westf?lische Wilhelms‐University, , Münster, Germany;2. Experimental Animal Research Centre, Medical Faculty of the Westf?lische Wilhelms‐University, , Münster, Germany;3. Department of Medical Informatics and Biomathematics, University of Münster, , Münster, Germany;4. Clinic of Exotic Pets, Reptiles, Exotic and Feral Birds, University of Hanover, , Hanover, Germany |
| Abstract: | |
| Keywords: | Amiodarone Dispersion of repolarization Torsade de pointes Acquired long QT syndrome Action potential morphology |
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