Synthesis of 1,3,4-thiadiazoles, imidazo[2,1-b]1,3,4-thiadiazoles and thiadiazolo[3,2-a]pyrimidines derived from benzimidazole as potential antimicrobial agents |
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| Authors: | F A Ashour N S Habib M el Taibbi S el Dine A S el Dine |
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| Affiliation: | Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt. |
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| Abstract: | ![]()
Several new 1,3,4-thiadiazole, imidazo[2,1-b]1,3,4-thiadiazole and thiadiazole[3,2-al]pyrimidine derivatives of benzimidazole were synthesized. The compounds were obtained from 1-ethyl or benzyl 2-(2-amino-1,3,4-thiadiazol-5-yl)thiomethylbenzimidazole. The antimicrobial activity of the prepared compounds was studied. |
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