益肾解痉汤治疗中风后肩-手综合征阴虚阳亢、脉络瘀阻型的疗效评价

目的评价益肾解痉汤治疗中风后肩-手综合征阴虚阳亢、脉络瘀阻型患者的疗效。方法将60例中风后肩-手综合征证属阴虚阳亢、脉络瘀阻型的住院患者按随机数字表法分为对照组和治疗组,每组各30例。对照组采用常规康复方案,治疗组在此基础上,加用益肾解痉汤50 mL,每日2次口服,两组均以1个月为1个疗程。分别在治疗前、治疗1个月后进行中风病、肩-手综合征疗效评价;通过神经功能缺损积分、中医证候诊断得分、Fugl-Meyer上肢运动功能（U-FMA）评价两纽患者神经功能缺损、中医证候及上肢运动功能改善情况,并观察用药不良反应。结果治疗组中风病临床治疗有效率为86.67%,肩-手综合征临床治疗有效率为90.00%,均高于对照组（P〈0.05）。两组治疗后神经功能缺损、中风病血瘀证、阴虚阳亢证中医证候及上肢运动功能均较治疗前明显改善（均P〈0.05）,且治疗组指标改善程度明显优于对照组（P〈0.05）。治疗中无不良反应发生。结论益肾解痉汤配合常规康复方案治疗中风后肩-手综合征疗效优于常规康复组。

Efficacy Assessment of Treating Post-stroke Shoulder-Hand Syndrome Patients of Yin Deficiency Yang Hyperactivity with Blood Stasis Stagnation Collaterals Syndrome by Yishen Tongluo Decoction

Objective To assess the efficacy of Yishen Jiejing Decoction（YJD） in treating poststroke shoulder-hand syndrome（SHS） patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome.Methods Totally 60 SHS patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome were randomly assigned to two groups,the treatment group and the control group,30 cases in each group.Conventional rehabilitation training and therapeutics were applied in all patients.Besides,patients in the treatment group took 50 mL YJD,twice a day.One month without interruption consisted of one course of treatment.The curative effects of each group were evaluated respectively before treatment and at one month after treatment.The neurologic impairment,TCM syndrome,and the improvement of upper limbs movement were assessed by the neurologic impairment integral,scoring for TCM syndrome diagnostics,Fugl-Meyer Assessment（U-FMA）.Adverse reactions were observed at the same time.Results The effective rate of stroke was 86.67%and the effective rate of SHS was 90.00%in the treatment group,higher than those of the control group（P〈0.05）.Both groups got improvement in neurologic impairment,stroke induced blood stasis syndrome,yin deficiency yang hyperactivity syndrome,and the improvement of upper limbs movement after treatment（all P〈0.05）.Besides,all the improvement was obviously superior in the treatment group（P〈0.05）.No adverse reaction occurred during the course of treatment.Conclusion The curative effect of YJD combined with conventional rehabilitation training was confirmative and superior to the control group.