体重指数与急性卒中患者住院期间肺部感染的关系研究

目的 探讨BMI与急性卒中患者住院期间发生肺部感染的关系。 方法 连续纳入2017年4月-2018年7月邯郸市第一医院神经内科收治的急性卒中患者，记录患者的 临床资料，按照是否发生肺部感染分为两组。采用多因素Logistic回归分析，探讨BMI及其他临床特征与 急性卒中患者住院期间发生肺部感染的关系。 结果 共纳入1073例急性卒中患者，平均年龄62.95±11.45岁，男性677例（63.1%）。其中56例 （5.2%）患者在住院期间发生了肺部感染。多因素Logistic回归分析显示，年龄（每增加1岁：OR 1.05， 95%CI 1.02～1.08，P =0.003）、BMI＜18.5 kg/m2（OR 2.51，95%CI 1.28～8.07，P =0.001）、水果摄入 量少（OR 2.10，95%CI 1.06～4.14，P =0.033）、发病时存在意识障碍（OR 8.65，95%CI 4.13～18.12，P ＜0.001）和吞咽障碍（OR 3.40，95%CI 1.67～6.94，P =0.001）是急性卒中患者住院期间发生肺部感染 的独立危险因素。 结论 BMI＜18.5 kg/m2是急性卒中患者住院期间发生肺部感染的独立危险因素。

Relationship between Body Mass Index and In-hospital Pneumonia in Acute Stroke Patients

Objective To investigate the relationship between BMI and in-hospital pneumonia in acute stroke
patients.
Methods Data of acute stroke patients who consecutively admitted to Handan First Hospital from
April 2017 to July 2018 were collected. Based on whether occurring in-hospital pneumonia, all the
patients were divided into pneumonia group and no-pneumonia group. Multivariate analysis was
performed to analyze the relationship between BMI and in-hospital pneumonia.
Results A total of 1073 acute stroke patients were enrolled into the study, with a mean age of
62.95±11.45 years old and 677 males (63.1%). Of all, 56 (5.2%) patients suffered from in-hospital
pneumonia. Multivariate analysis showed that age (1 year increase: OR 1.05, 95%CI 1.02-1.08,
P =0.003), BMI <18.5 kg/m2 (OR 2.51, 95%CI 1.28-8.07, P =0.001), less fruit intake (OR 2.10,
95%CI 1.06-4.14, P =0.033), disturbance of consciousness (OR 8.65, 95%CI 4.13-18.12, P <0.001)
and dysphagia (OR 3.40, 95%CI 1.67-6.94, P =0.001) were independent risk factors for in-hospital
pneumonia.
Conclusions BMI <18.5 kg/m2 was independent risk factors for in-hospital pneumonia in acute
stroke patients.