离子导入加味丹参饮联合常规医护措施治疗稳定型心绞痛临床研究

目的:观察加味丹参饮离子导入联合常规医护措施治疗稳定型心绞痛(SAP)心血瘀阻证的疗效。方法:选取本院收治的104例心血瘀阻型SAP患者,随机分为对照组与观察组各52例。2组患者均根据自身情况服用富马酸比索洛尔片、硝酸甘油片、阿司匹林肠溶片,控制血糖、血脂和血压,并施予健康教育、心理护理、生活饮食护理和用药护理指导等综合护理措施。观察组加予加味丹参饮离子导入治疗。2组疗程均为14 d。记录治疗前、治疗14 d后2组患者1周的心绞痛发作次数及每次发作的持续时间、硝酸甘油用量,检测心电图,评定心血瘀阻证评分和西雅图心绞痛量表(SAQ)评分。结果:治疗14 d后,观察组疗效优于对照组(P<0.05)。2组1周的心绞痛发作次数、心绞痛发作持续时间、硝酸甘油用量均较治疗前减少或缩短(P<0.01)。观察组心绞痛发作次数、心绞痛发作持续时间、硝酸甘油用量均少/短于对照组(P<0.01)。2组心血瘀阻证评分均较治疗前下降,SAQ评分均较治疗前升高,差异均有统计学意义(P<0.01)。观察组心血瘀阻证评分低于对照组、SAQ评分高于对照组,差异均有统计学意义(P<0.01)。结论:在常规医护措施基础上加用加味丹参饮离子导入治疗心血瘀阻型SAP,可进一步控制心绞痛的发作,减少心肌缺血,改善生活质量。

Clinical Study on Lontophoresis of Modified Danshen Yin Combined with Routine Nursing Measures for Stable Angina Pectoris

Objective:To observe the curative effect of lontophoresis of modified Danshen yin combined with routine nursing measures for stable angina pectoris(SAP)with the heart blood stasis syndrome.Methods:A total of 104 cases of SAP patients of the heart blood stasis type who were admitted and treated in our hospital were selected and randomly divided into the control group and the observation group,52 cases in each group.Based on their conditions,both groups were given various treatments:the oral administration of bisoprolol fumarate tablets,nitroglycerin tablets,and aspirin enteric-coated tablets;the control of blood glucose,blood lipid,and blood pressure;health education,mental nursing,nursing guidance of life and diet as well as medication,and other comprehensive nursing measures.The observation group was additionally treated with lontophoresis of modified Danshen yin.Both groups were treated for fourteen days.Before treatment and after fourteen-day treatment,the attack times of one week and duration of each angina pectoris,and the amount of nitroglycerin were recorded.Electrocardiogram was examined.The scores of the heart blood stasis syndrome and Seattle Angina Questionnaire(SAQ)were evaluated.Results:After fourteen-day treatment,the curative effect in the observation group was better than that in the control group(P<0.05).One week after fourteen-day treatment,the attack times of angina pectoris and the amount of nitroglycerin in the two groups were decreased when compared with those before treatment,and the duration of angina pectoris was shortened(P<0.01).The attack times of angina pectoris and the amount of nitroglycerin in the observation group were less than those in the control group,and the duration of angina pectoris was shorter(P<0.01).The scores of the heart blood stasis syndrome in the two groups were decreased when compared with those before treatment,and the SAQ scores were increased,differences being significant(P<0.01).The score of the heart blood stasis syndrome in the observation group was lower than that in the control group,and the SAQ score was higher,differences being significant(P<0.01). Conclusion:In the treatment of SAP of the heart blood stasis type,the additional lontophoresis ofmodified Danshen yin based on routine nursing measures can further control the attack of angina pectoris,relieve myocardialischemia,and improve quality of life.