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Role of CO(2) pneumoperitoneum-induced acidosis in CO(2) pneumoperitoneum-enhanced adhesion formation in mice |
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| Authors: | Molinas Carlos Roger Tjwa Marc Vanacker Bernard Binda Maria Mercedes Elkelani Osama Koninckx Philippe Robert |
| Affiliation: | a Departments of Obstetrics and Gynecologya and Anesthesiology, Leuven, Belgiumc c University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium b Center for Transgene Technology and Gene Therapy,b Flanders Interuniversity Institute for Biotechnology, Katholieke Universiteit Leuven, Leuven, Belgium |
| Abstract: | The effect of assisted ventilation and CO(2) pneumoperitoneum during laparoscopic surgery upon blood gases and adhesion formation were evaluated in mice. We confirmed that the CO(2) pneumoperitoneum induces acidosis and enhances adhesion formation, and an association between both effects was demonstrated, together with its modulation by the assisted ventilation. |
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