| 特异性靶向肝星状细胞治疗肝纤维化研究进展 |
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| 引用本文： | SUN Hua,李定国. 特异性靶向肝星状细胞治疗肝纤维化研究进展[J]. 国际消化病杂志, 2008, 28(2): 109-111 |
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| 作者姓名： | SUN Hua 李定国 |
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| 作者单位： | 上海交通大学医学院附属新华医院消化科,200092;上海交通大学医学院附属新华医院消化科,200092 |
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| 摘 要： | 肝纤维化是慢性肝病进展过程必经的一种病理组织学改变,而肝星状细胞的激活和增生是肝纤维化发生进展的中心环节.目前研究通过基因调控治疗及受体介导药物靶向肝星状细胞,可提高肝纤维化治疗的特异性,为临床应用开辟了新方向.
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| 关 键 词： | 靶向性 肝星状细胞 肝纤维化 |
Progress in specific-targeting hepatic stellate cell of liver fibrosis therapy |
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| SUN Hua,LI Ding-guo. Progress in specific-targeting hepatic stellate cell of liver fibrosis therapy[J]. International Journal of Digestive Disease, 2008, 28(2): 109-111 |
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| Authors: | SUN Hua LI Ding-guo |
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| Abstract: | Liver fibrosis is a chronic liver disease development process to go through a histological change.Hepatic stellate cell(HSC) is the central link in the activation and proliferation of liver fibrosis.Recent studies indicate that regulating gene therapy and receptor-mediated medicine can be used in targeting HSC,which will further improve liver specificity and develop new approach to clinical application. |
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| Keywords: | Specific-targeting Hepatic stellate cell Liver fibrosis |
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