蒙古族居民臀围与代谢综合征关系

目的探讨蒙古族居民臀围与代谢综合征(MS)的关系,为MS病因研究及其防治提供科学依据。方法采用整群抽样方法,对在内蒙古自治区通辽市科左后旗朝鲁吐苏木和奈曼旗固日班花苏木抽取的32个自然村2 534名蒙古族居民进行问卷调查、体格测量和生化检测。结果调查的2 534名蒙古族居民MS患病率为26.4%,标化患病率为17.1%;男性和女性的MS患病率分别为12.9%和26.4%;多因素非条件Logistic回归分析结果表明,女性、年龄≥30岁、C-反应蛋白对数值(LnCRP)≥1.372 mg/L、臀围≥88 cm和体质指数(BMI)≥24 kg/m2是蒙古族居民发生MS的独立危险因素;将调查对象分为无MS组分、1～2个MS组分和≥3个MS组分进行单因素无序多分类Logistic回归分析结果表明,随着臀围的增大,MS的危险性逐步增加,进一步调整年龄、性别、BMI和CRP后,与臀围<88 cm比较,臀围88～、92～和≥97 cm有1～2个MS组分与无组分比较的OR(95%CI)分别为1.191(0.884～1.605)、1.709(1.232～2.370)和2.646(1.538～4.551),且存在剂量反应关系(χ2趋势=18.046,P<0.001);有≥3个MS组分与无组分比较的OR(95%CI)分别为2.112(1.332～3.349)、4.910(3.084～7.820)和10.931(5.746～20.796),且存在剂量反应关系(χ2趋势=73.709,P<0.001)。结论臀围是蒙古族居民发生MS的连续独立危险因素。

Association of hip circumference with metabolic syndrome in Chinese Mongolian population

Objective To analyze the association of hip circumference(HC)with metabolic syndrome(MS) and to provide evidence for etiologic study and prevention of the disease.Methods With cluster-sampling method,a total of 2 589 Mongolian people in Tongliao city of Inner Mongolia were included in the study.Demographic data was collected;anthropometric indices and blood pressure were measured according to standard protocol.Biochemical analysis was conducted on fasting blood samples.Multinomial logistic regression was adopted to analyze the association of HC with MS.Results Binary logistic regression showed that after adjustment for age,gender,smoking,drinking,history of hypertension,body mass index(BMI),and C-reative protein(CRP),successive quartiles of HC were positively associated with MS,with the odds ratios(ORs)and 95% confidence interval(95%CI)of 1.000,2.365(1.299-4.307),5.777(3.302-10.107),and 12.594(7.008-22.630)for the residents with the HC of <88 cm,88-91 cm,92-96 cm,and ≥97 cm,respectively,and a dose-response relationship(trend test:P<0.001).Multinomial logistic regression showed positive association of HC with MS after adjustment for age,gender,BMI,and CRP.Compared to that of residents with the lowest quartile of HC,the OR for the residents with 1-2 components of MS were 1.191(0.884-1.605),1.709(1.232-2.370),and 2.646(1.538-4.551)and those for the residents with ≥3 components of MS were 2.112(1.332-3.349),4.910(3.084-7.820),and 10.931(5.746-20.796)for the HC quartiles of 88-91 cm,92-96 cm,and ≥97 cm,respectively,with dose-response relationships(trend test:P<0.001 for all).Conclusion High hip circumference was associated with a higher risk of MS among Mongolian residents in Inner Mongolia.