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东北刺人参挥发油抗真菌实验及临床研究
引用本文:付爱华 张宏桂. 东北刺人参挥发油抗真菌实验及临床研究[J]. 中华皮肤科杂志, 1997, 30(5): 310-311
作者姓名:付爱华 张宏桂
作者单位:白求恩医科大学第一临床学院皮肤科(付爱华,张林!130021),基础医学院普化教研室(张宏桂,刘松艳,吴广宣)
摘    要:
东北刺人参是主要分布于中国东北的药用植物。为充分利用长白山丰富资源,研制天然抗真菌新药,采用试管内药基法,对东北刺人参挥发油进行抗真菌实验研究。结果:它有很强的抗真菌活性,对常见皮肤癣菌有抑菌和杀菌作用,MIC为0.0625%~0.125%,MFC为0.125%~0.25%。用1%刺人参挥发油配制的霜剂对皮肤无刺激性,治疗皮肤癣菌病有效率达90%,值得今后进一步研究

关 键 词:东北刺人参  挥发油  皮肤癣菌  皮肤癣菌病

Clinical and Laboratory Studies of the Essential Oil from Oplopanax Elatus Nakai Against Fungi
Fu Aihua,Zhang Honggui,Zhang Ling,et al.. Clinical and Laboratory Studies of the Essential Oil from Oplopanax Elatus Nakai Against Fungi[J]. Chinese Journal of Dermatology, 1997, 30(5): 310-311
Authors:Fu Aihua  Zhang Honggui  Zhang Ling  et al.
Affiliation:Fu Aihua,Zhang Honggui,Zhang Ling,et al.Department of Dermatology,First Hospital of Norman Bethune Medical University,Changchun 130021
Abstract:
Oplopanax elatus Nakai,a medicinal plant,is mainly distributed in Northeast China.In order to make use of abundant resources of Chang Bai Shan,to make researches on natural anti fungal medicinal preparations,we studied the essential oil from Oplopanax elatus Nakai against fungi in vitro, the results showed that there was a marked antimycotic action of the essential oil. The MIC against common pathogenic dermatophytes ranged from 0 0625 0 125% and MFC 0 125 0 25%.1% cream of the essential oil was applied to the patients with dermatomycoses,the rate of effectiveness was 90%. This antifungal agent is purely natural, and shows no stimulation to the skin.
Keywords:Oplopanax elatus nakai Essential oil Dermatophytes Dermatomycoses
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