类风湿关节炎常用药物治疗方案及进展

类风湿性关节炎(RA)是一种以非化脓性增生性滑膜炎为主的对称性自身免疫性疾病,最初会影响小关节,逐渐发展为大关节,最后影响皮肤、眼睛、心脏、肾脏和肺部.RA发病机制特殊,目前虽诊疗手段繁多,却暂无完美诊疗手段.现有的用于治疗RA的药物诸如甲氨蝶呤类慢性抗风湿类药物(DMARDs)、类固醇(GC)、非类固醇消炎药(NSA...

Treatment and progress of common drugs for rheumatoid arthritis

Rheumatoid arthritis (RA) is a symmetric autoimmune disease dominated by non-suppurative proliferative synovitis, which initially affects small joints, gradually develops into large joints, and finally affects the skin, eyes, heart, kidney, and lung. The pathogenesis of RA is special. Although there are many diagnosis and treatment methods, there is no perfect diagnosis and treatment method. Existing drugs for the treatment of RA include disease-modifying anti-rheumatic drugs (DMARDs), steroids (GC), nonsteroidal anti-inflammatory drugs (NSAIDs), TNF inhibitors, and new drug carriers such as polymer colloids. Although traditional drugs have the advantages of explicit control of symptoms and adaptation range, they have significant side effects, especially GCs. In addition to these drugs for RA treatment, surgical treatment and other treatments such as psychological intervention therapy need to be studied. Therefore, this article does a brief review regarding the latest relevant documents in major literature databases.