| 抗癌剂鸦胆苦醇的含量测定及结构改造 |
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| 引用本文： | 李铣,王素贤,于荣敏,赵春菊,赵京芬,侯柏玲,朱廷儒.抗癌剂鸦胆苦醇的含量测定及结构改造[J].沈阳药科大学学报,1987(4). |
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| 作者姓名： | 李铣 王素贤 于荣敏 赵春菊 赵京芬 侯柏玲 朱廷儒 |
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| 作者单位： | 沈阳药学院天然药物研究室,沈阳药学院天然药物研究室,沈阳药学院天然药物研究室,沈阳药学院天然药物研究室,沈阳药学院天然药物研究室,沈阳药学院天然药物研究室,沈阳药学院天然药物研究室 中药系49期实习学生,中药系49期实习学生 |
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| 摘 要： | 应用双波长薄层扫描法测定了鸦胆子果实中鸦胆苦醇的含量;为降低毒性,增强活性,试验合成了双鸦胆苦醇丙二酸酯。
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| 关 键 词： | 鸦胆苦醇 双波长扫描 双鸦胆苦醇丙二酸酯 苦木科 |
THE CONTENT DETERMINATION AND STRUCTURE REFORM OF ANTITUMOR AGENT BRUSATOL |
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| Li Xian Yu Rongmin Wang Shuxjan Zhao Chunju Zhao Jingfen Hou Bailing Zhu Tingru Research.THE CONTENT DETERMINATION AND STRUCTURE REFORM OF ANTITUMOR AGENT BRUSATOL[J].Journal of Shenyang Pharmaceutical University,1987(4). |
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| Authors: | Li Xian Yu Rongmin Wang Shuxjan Zhao Chunju Zhao Jingfen Hou Bailing Zhu Tingru Research |
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| Institution: | Li Xian Yu Rongmin Wang Shuxjan Zhao Chunju Zhao Jingfen Hou Bailing Zhu Tingru Research Department of Natural Drugs |
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| Abstract: | Brusatol,which has proved to be a potential antitumor agent,was isolated from the traditional Chinese medicine "Yadanzi" (Brucea javanica(L.)Merr). The content (w/w) of brusatol in this plant was determined to be 2.7‰. The synthesis of 3,3-bisbrusatolyl malonate was carried out successfully. |
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| Keywords: | Brusatol Dual wavelength TLC scanner 3 3-bisbrusatolyl malonate Simaroubaceae |
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