大脑岛叶脑沟立体定位数据集的构建及平面回归分析

目的：构建岛叶重要脑沟基于连合间径定位体系中的立体定位数据集及其平面投影回归方程.方法：30名健康成人颅脑以连合间径（AC-PC）为扫描基线,获得的横断层MRI数据经格式转化后导入Photoshop软件,经过严格的图像配准,建立以AC-PC中点为原点的三维坐标系,获得大脑横断面图像上结构的三维立体坐标值,其中X值和Y值可直接在软件中读取,Z值为图像距离AC-PC平面的层数乘以图像层厚的积,分别测量岛叶中央沟最内侧点、前环岛沟和下环岛沟的坐标值,所有取样点坐标值组成岛叶脑沟在三维坐标系中的立体定位数据集.运用SPSS13.0软件,对所获得的数据进行统计,求解出在水平面、冠状面和矢状面上投影的回归方程.结果：成功构建岛叶中央沟、前、下环岛沟在三维坐标系中的立体定位数据集及各岛沟在各平面上的投影回归方程.结论：岛叶中央沟及前、下环岛沟进行立体定位数据集的构建,为立体定向和功能神经外科、三维放射治疗的应用提供解剖学基础;同时对于揭示位于大脑基底部岛叶及深部区域的发生、发育等形态学规律有重要的意义.

The planar regression analysis and building of the stereotatic data set of sulcus of the insula of human brain

Objective：To build the stereotactic data set and the planar regression equation of sulcus of the insula, based on the Descartes coordinate system which was set on the line between the anterior commissure and the posterior commissure. Methods：After the strict image registration, the coordinate system of the software coincides with the Descartes coordinate system based on AC-PC line were made. Then the coordinates of the central insular sulcus, the anterior periisular sulcus and the inferior periisular sulcus were recorded, the X-value and Y-value of the sample point was recorded directly from the software, the Z-value is the number of distance from recorded plane to the AC-PC plane. The stereotactic data set of the insular sulcus were constituted by all the coordinate values of sample points of insula,then the regression equations were fetched which were analysed by the SPSS13.0 software. Results ：The threedimensional stereotactic data set and the regression equation of the insular sulcus were constructed successfully. Conclusions： The construction of the insular stereotactic data set could provide anatomic basis for the application of stereotactic and functional neurosurgery,three-dimensional radiotherapy, and simultaneously uncovered the significant rules of the development of basilar parts of the human brain.