| Abstract: | ![]()
A cell membrane antigen was found in stable cell lines of epithelial origin, identical to an antigen in homogenates of the human gastric mucosa. The antigen was detected by means of antiserum against extracted membrane antigens of HeP-2 cells, absorbed by a mixture of homogenates of human lung, liver, and papillomas of the human larynx and breast. The antigen described was found in some of the adenocarcinomas of the stomach that were tested. It differs from Gold's carcinoembryonic antigen and from the secretory component of IgA, it is not the structural antigen of the D-type primate oncornavirus produced by HeP-2 cells and, evidently, it is not coded by the genome of that virus.Department of Etiology and Diagnosis of Tumors, N. F. Gamaleya Institute of Epidemiology and Microbiology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR G. V. Vygodchikov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 12, pp. 690–693, December, 1977. |
