180例住院患儿抗菌药物使用情况分析

目的：了解儿童医院住院患儿抗菌药物的使用情况，为儿童合理用药提供参考．方法根据某儿童医院住院患者抗菌药物使用情况调查表，采用回顾性调查法随机抽取2012年7月至12月住院患儿病历180份对抗菌药物的使用率、品种选择、用药频次、单次用药剂量、联合用药、预防用药时间、用药疗程等情况进行统计分析．结果180份病历中使用抗菌药物的为110例（61.1%），使用抗菌药物的病历中抗菌药物联合使用为55例（50%），使用频率最高的是头孢菌素类，其次是β-内酰胺＋酶抑制剂复合制剂.病历中出现用药频次不当的为12例（10.9%），单次剂量不当的为7例（6.4%），用药疗程不当的为9例（8.2%）.结论某儿童医院住院患儿抗菌药物的使用基本合理，但还存在品种选择不当、无指征使用、用法用量不当、疗程过长、联用不合理的情况，因此需加强抗菌药物的使用管理，提高抗菌药物临床合理应用水平．

Analysis of Antibiotics Usage in 180 cases in Pediatric Inpatients

Objective To realize the utilization of antibacterial drugs in pediatric inpatients in Children＇s Hospital for clinical reference of rational use of drugs. Methods By a retrospective study, 180 cases in pediatric inpatients were randomly sampled in Children＇s Hospital from July to December 2012, and were analyzed in utility rate, antibiotics varieties, administrational frequency,single dose,combination use,prophylaxis time,courses of drug use,etc. Results The use of antibacterial drugs in pediatric inpatients was 110 cases （61.1%） and used in combination was 55 cases （50%） . Leading the list in terms of DDDs was cephalosporins,followed byβ-lactam and its enzyme inhibitor complex preparations. The improper medications frequency was 12 cases （10.9%）, irrational single dose was 7 cases （6.4%）, and irrational course of treatment was 9 cases （8.2%） . Conclusion The utilization of antibacterial drugs in Children＇s Hospital is basically rational, but there still exist some irrational drug uses,such as antibiotics varieties,no indication, irrational dosage,long duration and irrational combination. So, it is necessary to enhance the administration of antibiotics use and improve the level of clinical reasonable application of antibiotics.