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Impact of COVID-19 in solid organ transplant recipients
Authors:Lara Danziger-Isakov  Emily A. Blumberg  Oriol Manuel  Martina Sester
Affiliation:1. Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, USA;2. Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA;3. Infectious Diseases Service and Transplantation Center, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland;4. Department of Transplant and Infection Immunology, Saarland University, Homburg, Germany
Abstract:
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exploded onto the world stage in early 2020. The impact on solid organ transplantation (SOT) has been profound affecting potential donors, candidates, and recipients. Importantly, decreased donations and the pressure of limited resources placed on health care by the pandemic also disrupted transplant systems. We address the impact of COVID-19 on organ transplantation globally and review current understanding of the epidemiology, outcomes, diagnosis, and treatment of COVID-19 in SOT recipients.
Keywords:antibiotic: antiviral  COVID-19  health services and outcomes research viewpoint  infectious disease  United infection and infectious agents - viral  immunosuppression / immune modulation  organ procurement  organ transplantation in general
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