Surgical considerations in infant lung transplantation: Challenges and opportunities |
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Authors: | John P. Costello Horacio G. Carvajal Aaron M. Abarbanell Pirooz Eghtesady Dilip S. Nath |
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Affiliation: | 1. Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London, UK;2. Section of Pediatric Cardiothoracic Surgery, St. Louis Children’s Hospital, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA |
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Abstract: | Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation. |
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Keywords: | artificial organs/ support devices: lung clinical research/ practice lung disease: congenital lung transplantation/ pulmonology pediatrics surgical technique |
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