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Surgical considerations in infant lung transplantation: Challenges and opportunities
Authors:John P. Costello  Horacio G. Carvajal  Aaron M. Abarbanell  Pirooz Eghtesady  Dilip S. Nath
Affiliation:1. Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London, UK;2. Section of Pediatric Cardiothoracic Surgery, St. Louis Children’s Hospital, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA
Abstract:
Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
Keywords:artificial organs/ support devices: lung  clinical research/ practice  lung disease: congenital  lung transplantation/ pulmonology  pediatrics  surgical technique
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