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Effect of rifampin on the pharmacokinetics,safety and tolerability of navitoclax (ABT‐263), a dual inhibitor of Bcl‐2 and Bcl‐XL,in patients with cancer
Authors:J. Yang  R. S. Pradhan  L. S. Rosen  A. M. Graham  K. D. Holen  H. Xiong
Affiliation:1. AbbVie Inc., , North Chicago, IL, USA;2. Alexion Pharmaceuticals, Inc., , Cheshire, CT, USA;3. UCLA Santa Monica Hematology‐Oncology, , Santa Monica, CA, USA
Abstract:
Keywords:Bcl‐2 inhibitor  CYP3A inducer  drug interaction  navitoclax  pharmacokinetics  rifampin
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