Rheumatoid neutrophilic dermatosis with tense blister formation: A case report and review of the literature |
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Authors: | Yumi Fujio MD Takeru Funakoshi MD Kaori Nakayama MD Masayuki Amagai MD Manabu Ohyama MD |
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Affiliation: | Department of Dermatology, Keio University School of Medicine, , Tokyo, Japan |
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Abstract: | We report a 78‐year‐old woman with rheumatoid neutrophilic dermatosis (RND) presenting with tense blisters; an extremely rare manifestation of this condition. Systemic corticosteroid was of limited efficacy, while dapsone was effective. A literature review of four similar cases showed that tense blisters in this type of RND tended to appear on the lower extremities of aged, female rheumatoid arthritis patients. Of note, half of the cases were resistant to corticosteroids, as anti‐neutrophil agents are reported to be effective. Accordingly, it is important to recognise this unusual manifestation for the timely initiation of appropriate therapy. |
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Keywords: | blister formation bullous pemphigoid neutrophilic dermatosis rheumatoid arthritis |
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