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| 吉西他滨联合顺铂治疗晚期乳腺癌的临床观察 | |
| 引用本文： | 王彩玲,王俊生. 吉西他滨联合顺铂治疗晚期乳腺癌的临床观察[J]. 中国肿瘤临床与康复, 2010, 0(1): 47-48 |
| 作者姓名： | 王彩玲 王俊生 |
| 作者单位： | 安阳市肿瘤医院; |
| 摘 要： | 目的观察吉西他滨联合顺铂治疗晚期乳腺癌的疗效及不良反应。方法47例晚期乳腺癌患者采用吉西他滨1000mg/m^2,静脉滴注30min,d1,d8;顺铂25～40mg/m^2,d2～4。21d一周期,治疗2周期后评价疗效及不良反应。结果47例均可评价疗效,共完成周期数为206个。完全缓解（CR）4例,部分缓解（PR）17例,稳定（SD）15例,进展（PD）11例,总有效率（CR＋PR）44.7%,疾病控制率（CR＋PR＋SD）76.6%,中位疾病进展时间8.7个月,中位生存期为12.3个月（2.0～52.5个月）。主要不良反应为骨髓抑制、胃肠道反应。结论吉西他滨联合顺铂治疗晚期乳腺癌疗效较好,毒副反应轻,耐受性好,是晚期乳腺癌的有效治疗方案。 |
| 关 键 词： | 吉西他滨 顺铂 乳腺肿瘤/化学疗法 |
Clinical observation of 47 patients with advanced breast cancer treated with gemcitabine combined with cisplatin |
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| WANG Cai-ling,WANG Jun-sheng. Clinical observation of 47 patients with advanced breast cancer treated with gemcitabine combined with cisplatin[J]. Chinese Journal of Clinical Oncology and Rehabilitation, 2010, 0(1): 47-48 | |
| Authors: | WANG Cai-ling WANG Jun-sheng |
| Affiliation: | WANG Cai-ling,WANG Jun-sheng(Anyang Tumor Hospital,Anyang 455000,China) |
| Abstract: | Objective To study the efficacy and toxic effects of gemcitabine combined with cisplatin in treating patients with advanced breast cancer.Methods Forty-seven patients with advanced breast cancer were treated with gemcitabine 1000 mg/m2 on day1and day8,cisplatin 25-40 mg/m2on days 2-4.The chemotherapy repeated every 3 weeks.Efficacy and toxic reactions were reviewed after 2 cycles of chemotherapy.Results Forty-seven patients were evaluable for response:CR 4 cases,PR 17cases,SD 15cases,and PD 11cases.The over... |
| Keywords: | Gemcitabine Cisplatin Breast neoplasms/chemotherapy |
| 本文献已被 CNKI 维普 等数据库收录！ | |