老年ACI患者治疗前后血浆leptin和血清Hcy、hs-CRP、IL-6检测的临床意义

目的：探讨了老年急性脑梗死（ACI）患者治疗前后血浆leptin和血清Hcy、hs-CRP和IL-6水平的变化及临床意义。方法：应用放射免疫分析、免疫法和免疫比浊法对33例老年ACI患者进行了血浆leptin和血清Hcy、hs-CRP、IL-6检测,并与35名正常健康人作比较。结果：老年ACI患者在治疗前血浆leptin和血清Hcy、hs-CRP和IL-6水平均非常显著地高于正常人组（P〈0.01）,经治疗3个月后与正常人组比较无显著性差异（P〉0.05）。结论：检测上述实验室项目,对老年ACI患者病情和进展的监测具有重要的临床价值。

Clinical Significance of Measurement on Plasma Leptin, Serum Hcy, hs-CRP,IL-6 Levels After Treatment in Elderly Patients with Acute Cerebral Infarction

Objective To study the significance of changes on plasma leptin and serum Hcy,Hs-CRP,IL-6 levels after treatment in elderly patients with acute cerebral infarction.Methods Plasma leptin and serum IL-6(with RIA) serum Hcy(with immune method).Serum hs-CRP(with high-sensitive turbidimetry) levels were measured in 33 elder patients with acute cerebral infarction and 35 normal controls.Results Before treatment,plasma leptin and serun Hcy,hs-CRP,IL-6 Levels were significantly higher in the patients than those in controls.(P<0.01).after treatment for 3 months,the levels of these laboratory items in patients were no more difference from those in controls(P>0.05).Conclusion Detection of above-mentioned laboratory test might possess important value to monitor the pathosis and progress of disease in elderly patients with ACI.