| 急性脑梗死患者治疗前后血清Hcy、hs-CRP、SOD和MDA检测的临床意义 |
| |
| 引用本文： | 吴秀珍,陈方方. 急性脑梗死患者治疗前后血清Hcy、hs-CRP、SOD和MDA检测的临床意义[J]. 放射免疫学杂志, 2012, 25(4): 388-390. DOI: 10.3969/j.issn.1008-9810.2012.04.012 |
| |
| 作者姓名： | 吴秀珍 陈方方 |
| |
| 作者单位： | 1.新疆医科大学第五附属医院神经内科,830011;2.新疆医科大学第五附属医院神经内科,830011 |
| |
| 摘 要： | 目的:探讨了急性脑梗死(ACI)患者治疗前后血清Hcy、hs-CRP、SOD和MDA水平的变化及临床意义.方法:分别应用放免法、酶联法、化学法和免疫比浊法对32例ACI患者进行了治疗前后血清Hcy、hs-CRP、SOD和MDA检测,并与35名健康人作比较.结果:ACI患者在治疗前血清Hcy、hs-CRP和MDA水平非常显著地高于正常人组(P＜0.01),而SOD水平则低于正常人组(P＜0.01),经治疗2周后与正常人组比较则无显著性差异(P＞0.05).结论:ACI的发生和发展与血清Hcy、hs-CRP、SOD和MDA水平密切相关.
|
| 关 键 词： | 急性脑梗死 同型半胱氨酸 超敏C-反应蛋白 超氧化物歧化酶 丙二醛 |
Clinical Significance of Changes on Serum Hcy, hs-CRP, SOD and MDA Levels Both Before and After Treatment in Patients with Acute Cerebral Infarction |
| |
| Wu Xiu-zhen , Chen Fang-fang. Clinical Significance of Changes on Serum Hcy, hs-CRP, SOD and MDA Levels Both Before and After Treatment in Patients with Acute Cerebral Infarction[J]. Journal of Radioimmanology, 2012, 25(4): 388-390. DOI: 10.3969/j.issn.1008-9810.2012.04.012 |
| |
| Authors: | Wu Xiu-zhen Chen Fang-fang |
| |
| Affiliation: | Department of Neurology,the Fifth Affiliated Hospital of Xinjiang Medical University,Wulumuqi(830011),China |
| |
| Abstract: | Objective To explore the clinical significance of changes on serum Hcy,hs-CRP,SOD and MDA levels both before and after treatment in patients with acute cerebral infarction(ACI).Methods Serum Hcy(with ELISA),SOD(with RIA),MDA(with chemistry),hs-CRP(with immunoturbidimetry) levels were measured in 32 patients with acute cerebral infarction and compared with 35 normal controls.Results Before treatment,serum Hcy,hs-CRP,MDA levels were significantly higher than those in controls(P<0.01),while the serum SOD level was distinctly lower(P<0.01).After treatment for 2 weeks,the levels dropped markedly to approaching normal vs control(P>0.05).Conclusion Serum Hcy,hs-CRP,SOD and MDA levels were closely correlated to the progress of acute cerebral infarction. |
| |
| Keywords: | acute cerebral infarction(ACI) high sensitivity C-reactive protein(hs-CRP) homocysteine(Hcy) superoxide dismutase(SOD) malondialdehyde(MDA) |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
