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ACI患者治疗前后血浆ET-1和血清Hcy、11,-6检测的临床意义
引用本文:陈方方,吴秀珍. ACI患者治疗前后血浆ET-1和血清Hcy、11,-6检测的临床意义[J]. 放射免疫学杂志, 2012, 25(2): 124-125
作者姓名:陈方方  吴秀珍
作者单位:新疆医科大学第五附属医院神经内科,830011
摘    要:目的:探讨急性脑梗死(ACI)患者治疗前后血浆ET-1和血清Hcy、IL-6水平的变化及意义。方法:应用放射免疫分析和酶联法对33例ACI患者进行了治疗前后血浆ET-1和血清Hcy、IL-6检测,并与35例正常健康人作比较。结果:ACI患者治疗前血浆ET.1和血清Hey、IL-6水平非常显著地高于正常人组(P〈0.01),经治疗2周后与正常人组比较无显著性差异(P〉0.05)。结论:检测ACI患者治疗前后血浆ET.1和血清Hcy、IL-6水平的变化有助于对治疗效果和预后的监察。

关 键 词:急性脑梗死内皮素-1  同型半胱氨酸白细胞介素-6

Clinical Significance of Changes of Plasma ET-1 and Serum Hcy,IL-6 Levels After Treatment in Patients with Acute Cerebral Infarction
Chen Fang-fang , Wu Xiu-zhen. Clinical Significance of Changes of Plasma ET-1 and Serum Hcy,IL-6 Levels After Treatment in Patients with Acute Cerebral Infarction[J]. Journal of Radioimmanology, 2012, 25(2): 124-125
Authors:Chen Fang-fang    Wu Xiu-zhen
Affiliation:Department of Neurology,The Fifth Affiliated Hospital of Xinjiang Medical University,Wulumuqi(830011),China
Abstract:Objective To explore the significance of changes of plasma ET-1 and serum Hey,IL-6 levels after treatment in patients with acute cerebral infarction.Methods Plasma ET-1,serum IL-6(both with RIA) and serum Hcy(with ELISA) levels were measured in 33 patients with acute cerebral infarction and 35 normal controls.Results Before treatment,the plasma ET-1 and serum Hey,IL-6 levels in the patients were significantly higher than those in controls(P <0.01),after treatment for 2 weeks,plasma ET-1 and serum Hey,IL-6 levels were no significant difference(P>0.05).Conclusion Detection the changes of plasma ET-1 and serum Hey,EL-6 levels after treatment in patients with acute cerebral infarction might be helpful to monitor efficacy of therapy and prognosis.
Keywords:acute cerebral infarction(ACI)  endothelin-l(ET-1)  homocysteine(Hey)  interleukin-6(IL-6)
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