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妊高征患者治疗前后血浆leptin和血清Hcy、NPY检测的临床价值
引用本文:陈晓超. 妊高征患者治疗前后血浆leptin和血清Hcy、NPY检测的临床价值[J]. 放射免疫学杂志, 2012, 25(2): 138-140. DOI: 10.3969/j.issn.1008-9810.2012.02.010
作者姓名:陈晓超
作者单位:江苏省沭阳县人民医院妇产科,223600
摘    要:目的:探讨了妊高征患者治疗前后血浆leptin和血清Hcy、NPY水平的变化及临床意义.方法:应用放免法和酶联法对33例妊高征患者进行了治疗前后血浆leptin和血清Hcy、NPY检测,并与35例正常健康人作比较.结果:妊高征患者在治疗前血浆leptin和血清Hcy、NPY均非常显著地高于正常人组(P<0.01),经治疗1个月后与正常人组比较仍有显著性差异(P<0.05).结论:检测妊高征患者血浆leptin和血清Hcy、NPY水平的变化已被认可用于疗效观察和预后判断.

关 键 词:妊高征  瘦素  同型半胱氨酸  神经肽Y

Clinical Evaluation of Determination the Changes of Plasma Leptin,Serum Hcy and NPY Levels After Treatment in Patients with Pregnancy Induced Hypertension(PIH)
Chen Xiao-chao. Clinical Evaluation of Determination the Changes of Plasma Leptin,Serum Hcy and NPY Levels After Treatment in Patients with Pregnancy Induced Hypertension(PIH)[J]. Journal of Radioimmanology, 2012, 25(2): 138-140. DOI: 10.3969/j.issn.1008-9810.2012.02.010
Authors:Chen Xiao-chao
Affiliation:Chen Xiao-chao Department of Obstetrics and Gynecology,Shuyang County People’s Hospital,Shuyang(223600),China
Abstract:Objective To explore the clinical significance of changes on plasma leptin,serum Hey and NPY levels after treatment in patients with pregnancy induced hypertension(PIH).Methods plasma leptin,serum NPY(with RIA ) and Hey(with ELISA),levels were determined in 33 patients with PIH both before and after treatment as well as in 35 normal controls.Results Be- fore treatment plasma leptin and serum Hey,NPY levels in patients with PIH were significantly higher than those in controls(P < 0.01).After 1 month of treatment the levels dropped markedly but still remained notably higher(P < 0.05).Conclusion Plasma leptin,serum Hey and NPY levels were closely related to the diseases of PIH.Such changes has been recognized to be used observing efficacy of therapy and prognosis.
Keywords:pregnancy induced hypertension(PIH)  homocysteine(Hey)  neuropeptide Y
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