过敏性鼻炎患儿过敏原特异性IgE检测与临床意义

目的 了解过敏性鼻炎儿童主要过敏原分布情况及特点,以指导临床防治.方法 采用免疫印迹法体外定量检测患儿血清中特异性IgE抗体及20种常见过敏原.结果 938例过敏性鼻炎患儿中,100%至少对一种以上的过敏原呈阳性反应,其中487例患儿总IgE〉400IU/Ml,230例患儿总IgE在200IU/ml~400IU/ml之间.在检测20种过敏原中以户尘螨和屋尘的阳性率最高（90.0%,80.8%）.结论 过敏性鼻炎患儿至少有一种特异性IgE抗体显著增加,户尘螨、屋尘、动物皮屑、羊肉和牛奶是引起儿童过敏性鼻炎的主要过敏原.儿童在春秋温暖季节易发过敏性鼻炎.

Detection of Specific IgE in Serum of Children with Allergic Rhinitis and Its Clinical Significance

Objective To investigate the main allergen distribution and characteristic in the children with allergic rhinitis,as to guide the clinical prevention and treatment.Methods 938 cases with allergic rhinitis used immune print detecting the special IgE antibody and twenty kinds of common allergen in serum.Results In 938 cases with allergic rhinitis there were a positive result for special allergen at least.Among them the total IgE of 487 cases were more than 400IU/ml,the total IgE of 230 cases were between 200 and 400 IU/ml.In 20 common allergen,the leading allergen was house dust and mite,the positive results were 90.0% and 80.8%.Conclusion The children with allergic rhinitis were more than one kind positive of specific allergen.The main allergens for the children with allergic rhinitis were house dust,dust mite,pet skin scraps,mutton and milk etc.The spring and autumn season caused easily allergic rhinitis in children.