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卵巢癌患者血清Hcy、HFA和SA联检的临床意义
引用本文:陈晓超. 卵巢癌患者血清Hcy、HFA和SA联检的临床意义[J]. 放射免疫学杂志, 2012, 25(2): 187-188
作者姓名:陈晓超
作者单位:江苏省沭阳县人民医院妇产科,223600
摘    要:
目的:探讨了卵巢癌患者血清Hcy、HE4和sA联检的变化及临床意义。方法:应用酶联法和生化法对33例卵巢癌患者进行了血清Hcy、HFA和sA的检测,并与35例正常健康人作比较。结果:卵巢癌患者血清Hcy、HE4和SA水平均非常显著地高于正常人组(P〈0.01)。且血清Hcy水平与HE4、SA水平呈正相关(r=0.6128、0.5942,P〈0.01)。结论:检测卵巢癌患者血清Hcy、HFA和SA水平的变化,提示该类生物标志物的变化,有助于对疾病早期诊断和适宜的预后。

关 键 词:卵巢癌  同型半胱氨酸  人附睾蛋白4  唾液酸

Clinical Significance of Combined Detection of Serum Hcy,HE4 and SA Levels in Patients with Ovarian Cancer
Chen Xiao-chao. Clinical Significance of Combined Detection of Serum Hcy,HE4 and SA Levels in Patients with Ovarian Cancer[J]. Journal of Radioimmanology, 2012, 25(2): 187-188
Authors:Chen Xiao-chao
Affiliation:Chen Xiao-chao Shuyang People’s Hospital,Shuyang(223600),China
Abstract:
Objective To explore the significance of changes of serum Hcy,H£4 and SA levels in patients with ovarian cancer. Methods Serum Hey,HE4(with ELISA),SA(with Biochemistry) levels were determined in 33 patients with ovarian cancer and 35 normal healthy controls.Results Serum Hey,HE4 and SA levels were significantly higher in the patients than that of controls(P < 0.01).Serum Hey levels were positively correlated with serum HE4,SA levels in patients with ovarian cancer(r = 0.6128,0.5942, P <0.01).Conclusion Detection of serum Hey,HE4 and SA levels it suggested the changes of these biomarkers will be helpful for the early diagnosis and favourable prognosis.
Keywords:ovarian cancer  homocysteine(Hey)  human epididymis protein 4(HE4)  sialic acid(SA)
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