Expression of early growth response-1 in human gastric cancer and its relationship with tumor cell behaviors and prognosis |
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| Authors: | Eun Myung Young-Lan Park Nuri Kim Cho-Yun ChungHyun-Bum Park Hyung-Chul ParkDae-Sung Myung Jong-Sun KimSung-Bum Cho Wan-Sik LeeYoung-Eun Joo |
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| Affiliation: | Department of Internal Medicine, Chonnam National University Medical School, Gwangju 501-757, Republic of Korea |
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| Abstract: | The early growth response-1 (Egr-1) is crucial in many cell regulatory processes related to the progression of human cancers. Its overexpression has been demonstrated in variable human cancers and may have prognostic significance. The aims of this current study were to evaluate whether Egr-1 affects invasive and oncogenic phenotypes of human gastric cancer cells, and to examine the relationships between its expression and various clinicopathological parameters, including survival in human gastric cancer patients. |
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| Keywords: | Egr-1 Stomach neoplasm Tumor behaviors Prognosis |
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