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Detection of ectopic thyroid remnants: A serious diagnostic dilemma. When molecular biology and immunohistochemistry can solve the problem
Authors:Esther Diana Rossi  Maurizio MartiniPatrizia Straccia  Luigi Maria LaroccaGuido Fadda
Affiliation:Division of Anatomic Pathology and Histology, Università Cattolica del Sacro Cuore, “Agostino Gemelli” School of Medicine and Hospital, Rome, Italy
Abstract:
The presence of ectopic thyroid tissue is a frequent diagnostic feedback related to a possible histogenetic abnormality or a result of post-surgical seeding. The important challenge is the diagnostic definition of its nature, which could lead to a different therapeutic approach. We describe a case with all the possible implications and differential diagnoses supported by the application of immunohistochemistry and BRAF-V600E molecular detection.
Keywords:Tall cell papillary thyroid carcinoma   Ectopic thyroid tissue   Immunohistochemistry   Molecular biology
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