|
|||||
|
|
Mathematical model to analyse urea synthesis following alanine infusion in control subjects and in patients with liver cirrhosis |
|
| Authors: | R Bolzani G P Bianchi G Marchesini E Sarti |
| Institution: | (1) Istituto di Clinica Oculistica, Università di Modena, Via Università 4, 41100 Modena, Italy;(2) Istituto di Clinica Medica, Università di Bologna, via Massarenti 9, 40126 Bologna, Italy;(3) Dipartimento di Elettronica Informatica e Sistemistica, Università di Bologna, Viale Risorgimento 2, 40136 Bologna, Italy |
| Abstract: | A three-compartment model was used to analyse the urea response to an alanine infusion in control subjects and patients with liver cirrhosis. Discriminant analysis showed a good separation between model coefficients of the two groups. A single parameter was derived, able to quantify the liver functional capacity. The method provides a useful diagnostic tool in patients with liver disease. |
| Keywords: | Alanine Liver cirrhosis Mathematical model Urea |
| 本文献已被 SpringerLink 等数据库收录！ | |