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Antidiabetic activity of 50% ethanolic extract of Ricinus communis and its purified fractions
Authors:Poonam Shokeen  Prachi AnandY. Krishna Murali  Vibha Tandon
Affiliation:Medicinal Chemistry Research Laboratory, Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi, Delhi 110 007, India
Abstract:
We investigated the antidiabetic activity of 50% ethanolic extract of roots of Ricinus communis (RCRE) along with its bioassay-guided purification. Five-hundred milligram per kilogram body weight appeared to be the effective dose as it caused the maximum lowering of the fasting blood glucose, both in normal as well as type 1 diabetic animals. The maximum hypoglycemic effect was always observed at the 8th h up to which the study has been conducted.
Keywords:Diabetes   Ricinus communis   Antidiabetic   Alloxan
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