Calcium channel blockers and prostate cancer |
| |
| Authors: | Kevin R. Loughlin |
| |
| Affiliation: | Division of Urology, Department of Surgery, Brigham and Women''s Hospital, Harvard Medical School, Boston, MA |
| |
| Abstract: | The relationship between calcium channel blockers and prostate cancer has been an area of increased interest to investigators. Calcium channel blockers have been shown to influence cell proliferation, differentiation, and apoptosis. Clinically, the association between calcium channel blockers and the development of prostate cancer has been controversial. However, on a basic science level, there is evidence that calcium channel blockers induce cytotoxicity in androgen receptor positive cell lines and may offer an innovative strategy for the treatment of castration-resistant prostate cancer. |
| |
| Keywords: | Calcium channel blockers Prostate cancer |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
