高强度军事训练致非创伤性肾损伤相关因素分析

目的了解高强度军事训练后不同军龄及训练场地对训练后非创伤性肾损伤发生率的影响。方法1320名海军陆战队官兵进行5kin武装越野后，以干化学法检测尿中蛋白及血红蛋白；尿液离心后镜检红细胞；以酶联免疫吸附法（ELISA）检测尿N-乙酰-8-D-氨基葡萄糖苷水解酶（NAG）和尿视黄醇结合蛋白（RBP）；对各项检验结果进行不同军龄及训练场地间的对比分析。结果训练后血尿发生率为2．1％，血红蛋白尿为7．4％，蛋白尿为44％，尿NAG异常为57．1％，尿RBP异常为57．3％。军龄小于1年者与1年以上者有统计学差异（P〈0．05），军龄1年以上者之间无统计学差异（P〉0．05）。不同训练场地的部队在尿NAG、RBP比较中存在差异（P〈0．05）。结论高强度军事训练后非创伤性肾损伤的发生率较高，与不同军龄及训练场地有关。

Related factors for non-traumatic renal injury occurrence due to high intensity military training

Objective To investigate the influence of different years of military service and training fields on the incidence of nontraumatic renal injury due to high intensity military training. Methods A total of 1 320 officers and men from marines were enrolled in the present study. Proteinuria and hemoglobinuria were detected by dry chemistry test strips after five-kilometer armed crosscountry race. Positive hematuria was observed under microscope after centrifugation of urine samples. Retinol-binding protein （RBP） and N-acetyl- β -D-glucosaminidase （NAG） were detected by enzyme linked immunosorbent assay （ELISA）. The results obtained from the officers and men of marines were compared and analyzed. Results The incidence rate of hematuria, proteinuria, hemoglobinuria, NAG, and RBP was 2.1%, 7.4%, 44 %, 57.1%, and 57.3%, respectively. There was a difference in the incidence rate of the above abnormalities between those with less than 1 year of military service and those with more than 1 year of military service （P〈0.05）, but no difference between those with more than 1 year of military service （P〉0.05）. The incidence of NAG and RBP was significantly different between those after training in different fields （P〈0.05）. Conclusion The incidence of renal injury high intensity military training is relatively high and correlates to different years of military service and training fields.