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左甲状腺素钠的药物相互作用及机制初探
引用本文:李中东,施孝金,王宏图. 左甲状腺素钠的药物相互作用及机制初探[J]. 药学服务与研究, 2003, 3(1): 59-61
作者姓名:李中东  施孝金  王宏图
作者单位:复旦大学附属华山医院药剂科,上海,200040
摘    要:目的:对左甲状腺素钠的药物相互作用及机制作一综述,供临床用药时参考。方法:查阅国内外献,从影响左甲状腺素浓度的药物和左甲状腺素钠对其他药物的影响两个方面探讨了左甲状腺素与其他药物之间的相互作用及可能机制。结果:通过分折,对左甲状腺素与其有相互作用的其他药物合用时,提出了具体的用药建议。结论:左甲状腺素钠的药物相互作用值得关注,以减少可避免的不良后果。

关 键 词:左甲状腺素钠 药物相互作用 硫糖铝 抗酸剂
文章编号:1671-2838(2003)01-0059-03
修稿时间:2002-04-10

The drug interactions and mechanism of levothyroxine sodium with other drugs
LI Zhong-Dong,SHI Xiao-Jin,WANG Hong-Tu. The drug interactions and mechanism of levothyroxine sodium with other drugs[J]. Pharmaceutical Care and Research, 2003, 3(1): 59-61
Authors:LI Zhong-Dong  SHI Xiao-Jin  WANG Hong-Tu
Abstract:Objective:To review the literature of interations of levothyroxine sodium with other drugs in order to provide reference for clinical professionals in the practice of drug therapy. Methods: The related Chinese and foreign literature were collected. The drug interaction and mechanism of interaction of levothyroxine sodium with other drugs were discussed from two aspects, ie. the drugs affecting levothyroxine's concentration and other drugs' concentration affected by levothyroxine. Results:Practical suggestions were proposed according to the interaction of levothyroxine with other drugs. Conclusion:Attention should be paid to the drug interactions between levothyroxine and other drugs in order to decrease evitable adverse effect.
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