| FD-1冷冻干燥机的研制及生物材料的冷冻干燥 |
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| 引用本文： | 吴志谷,耿淼,孙同柱,付小兵,熊德鑫,乔迎伍,宋月金,孙世学,盛志勇.FD-1冷冻干燥机的研制及生物材料的冷冻干燥[J].生物医学工程学杂志,2004,21(3):460-463. |
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| 作者姓名： | 吴志谷 耿淼 孙同柱 付小兵 熊德鑫 乔迎伍 宋月金 孙世学 盛志勇 |
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| 作者单位： | 解放军第304医院,全军烧伤研究所,基础部,北京,100037 |
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| 摘 要： | 观察自制冷冻干燥机冷冻干燥生物材料的效果。采用 R5 0 2压缩机和制冷剂制成 FD- 1冷冻干燥机。本实验冷冻干燥了胶原海绵、菌种及去纤酶。在冻干箱负载或空载情况下蒸发冷凝器温度均可达到 - 4 5℃ ,小冰箱可达到 - 30℃ ,冻干的胶原海绵具有许多孔洞的结构 ,冻干的菌种和去纤酶性能保持良好。 FD- 1冷冻干燥机适用于生物样品中小批量的冷冻干燥
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| 关 键 词： | 冷冻干燥机 冷冻干燥 胶原海绵 菌种 生物材料 |
Development of a Freezing Drier for Lyophilization of Biomaterials |
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| Zhigu Wu,Miao Gen,Tongzhu Sun,Xiaobing Fu,Dexin Xiong,Yingwu Qiao,Yuejin Song,Shixue Sun,Zhiyong Sheng.Development of a Freezing Drier for Lyophilization of Biomaterials[J].Journal of Biomedical Engineering,2004,21(3):460-463. |
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| Authors: | Zhigu Wu Miao Gen Tongzhu Sun Xiaobing Fu Dexin Xiong Yingwu Qiao Yuejin Song Shixue Sun Zhiyong Sheng |
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| Institution: | Research Department of Burn Institute, 304th Hospital, Beijing 100037, China. wuzg@cyw.net.cn |
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| Abstract: | To observe and assess the performance and effect of our self-made FD-1 freezing drier on biomaterials. R502 compressor and R502 refrigerating agent were adopted. In the experiment, FD-1 lyophilized collagen sponge, strain and defibrinogenase. The evaporating-condenser temperature reached -45 degrees C and the small icebox temperature reached -30 degrees C under the loading or free-loading circumstances in the lyophilizing box. The lyophilized collagen sponge had many pores in the structure, and the strain and the defibrinogenase were lyophilized and maintained satisfactorily. This freezing drier is suitable for lyophilizing some biomaterial samples in small or medium batches. |
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| Keywords: | Freezing drier Lyophilization Collagen sponge Strain Biomaterial |
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