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N末端脑钠肽原在心血管疾病诊治及预后中的应用进展
引用本文:黄裕立,吴焱贤. N末端脑钠肽原在心血管疾病诊治及预后中的应用进展[J]. 国外医学:内科学分册, 2009, 36(2): 74-77
作者姓名:黄裕立  吴焱贤
作者单位:南方医科大学附属顺德第一人民医院,广东,顺德,523800;南方医科大学附属顺德第一人民医院,广东,顺德,523800
摘    要:脑钠肽(BNP)是一种主要从心室分泌的多肽类激素,在心脏维持其结构和功能的正常中起着重要的代偿作用,其同源代谢产物N末端脑钠肽原(NT—proBNP)具有半衰期长、稳定性良好等优点,临床测定血浆NT-proBNP水平有助于呼吸困难的鉴别诊断,同时可用于对心血管疾病尤其是急慢性心力衰竭的疗效、预后评估及指导治疗。本文就NT—proBNP在心血管疾病尤其是充血性心力衰竭的诊断、治疗及预后中的应用作一综述。

关 键 词:N末端脑钠肽原  充血性心力衰竭  诊断  预后

Application of N-terminal pro-B-type natriuretic peptide in diagnosis,treatment and prognosis of cardiovascular disease
HUANG Yu-li,WU Yan-xian. Application of N-terminal pro-B-type natriuretic peptide in diagnosis,treatment and prognosis of cardiovascular disease[J]. Foreign Medical Sciences(Section of Internal Medicine), 2009, 36(2): 74-77
Authors:HUANG Yu-li  WU Yan-xian
Affiliation:HUANG Yu-li,WU Yan-xian. Department of Cardiology,The Shunde Affiliated Hospital,Southern Medical University,Shunde 523800,China
Abstract:Brain natriuretic peptide(BNP) is secreted by cardiomyocytes and plays an important role in the maintenance of cardiac structure and function. N-terminal pro-B-type natriuretic peptide(NT-proBNP) is the inactive metabolite of BNP, and it has a longer halftime and better stability than BNP. The detection of NT-proBNP plays an important role in the differential diagnosis of acute dyspnea, meanwhile, it can be used in the diagnosis, treatment and prognosis of cardiovascular diseases, especially in congestive h...
Keywords:NT-proBNP  Congestive heart failure  Diagnosis  Prognosis  
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