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肥胖对OSAHS患者甲状腺功能影响机制的研究进展
引用本文:章华沁,郑艳文,邬海燕.肥胖对OSAHS患者甲状腺功能影响机制的研究进展[J].国际医药卫生导报,2022,28(1):75-78.
作者姓名:章华沁  郑艳文  邬海燕
作者单位:1金华市第五医院内科,金华 321000; 2杭州市萧山区第一人民医院呼吸科,杭州 311200
基金项目:杭州市科技计划引导项目(20171226Y90); 杭州市萧山区重大科技攻关项目(2018209)
摘    要:阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)属于临床医学中常见的睡眠病症,从相关研究报道来看,肥胖对该疾病的危险性是最高的。而该疾病与甲状腺功能之间的联系还不是十分明确,但是OSAHS患者中有一部分同时存在甲状腺功能减退情况,有学者认为...

关 键 词:阻塞性睡眠呼吸暂停低通气综合征  肥胖  甲状腺功能
收稿时间:2021-09-06

Mechanism of obesity influencing thyroid function in patients with obstructive sleep apnea hypopnea syndrome
Zhang Huaqin,Zheng Yanwen,Wu Haiyan.Mechanism of obesity influencing thyroid function in patients with obstructive sleep apnea hypopnea syndrome[J].International Medicine & Health Guidance News,2022,28(1):75-78.
Authors:Zhang Huaqin  Zheng Yanwen  Wu Haiyan
Institution:1Department of Internal Medicine, Fifth Hospital of Jinhua City, Jinhua 321000, China;  2Department of Respiratory, Xiaoshan District First People's Hospital, Hangzhou 311200, China
Abstract:Obstructive sleep apnea hypopnea syndrome (OSAHS), also known as obstructive sleep apnea hypopnea syndrome, is a common sleep disorder in clinical medicine. According to relevant research reports, obesity is the highest risk factor for OSAHS. The relationship between the disease and thyroid function is not very clear, but some patients with OSAHS have hypothyroidism at the same time. Some scholars believe that this is not different from the incidence of hypothyroidism in the general population. At the same time, some scholars believe that obese patients with OSAHS and children with OSAHS have high risk of hypothyroidism. At present, the influence mechanism of obesity on thyroid function in OSAHS patients is still unclear. OSAHS patients are prone to recurrent apnea, hypoventilation, and micro arousal during sleep, leading to hypoxia. Obesity aggravates hypoxia and causes metabolic disorder, insulin resistance, and leptin, adiponectin, and functional changes. The change of vitamin D level can cause the change of thyroid function. Abnormal nerve regulation and inflammatory reaction can cause the change of thyroid function. In addition, obesity itself can also lead to changes in thyroid function. This article explores the mechanism of obesity on thyroid function in patients with OSAHS.
Keywords:Obstructive sleep apnea hypopnea syndrome  Obesity  Thyroid function
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