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牙周干预对2型糖尿病伴慢性牙周炎患者血清炎症因子影响的Meta分析
引用本文:侯玉,康帅,刘正雅,连伟,魏巍,王淑敏,李俊玲,王璐璐. 牙周干预对2型糖尿病伴慢性牙周炎患者血清炎症因子影响的Meta分析[J]. 实用口腔医学杂志, 2021, 0(2): 232-236
作者姓名:侯玉  康帅  刘正雅  连伟  魏巍  王淑敏  李俊玲  王璐璐
作者单位:解放军联勤保障部队第九八九医院口腔科;解放军联勤保障部队第九八九医院消化内科
基金项目:洛阳市科技计划项目(编号:1810004A)。
摘    要:
目的:系统评价牙周干预对2型糖尿病伴慢性牙周炎患者血清炎症因子的作用.方法:检索中国期刊全文数据库、万方数据库、维普数据库、中国科技期刊数据库、中国生物医学文献数据库、Pubmed、Cochrane library、ScienceDirect和Embase等.统计分析采用Revman 5.3版软件.结果:共纳入12个R...

关 键 词:牙周干预  2型糖尿病  慢性牙周炎  炎症因子  Meta分析

The efficacy of periodontal intervention on serum inflammatory cytokine levels in type 2 diabetic patients with chronic periodontitis: A Meta-Analysis
HOU Yu,KANG Shuai,LIU Zhengya,LIAN Wei,WEI Wei,WANG Shumin,LI Junling,WANG Lulu. The efficacy of periodontal intervention on serum inflammatory cytokine levels in type 2 diabetic patients with chronic periodontitis: A Meta-Analysis[J]. Journal of Practical Stomatology, 2021, 0(2): 232-236
Authors:HOU Yu  KANG Shuai  LIU Zhengya  LIAN Wei  WEI Wei  WANG Shumin  LI Junling  WANG Lulu
Affiliation:(Department of Oral Medicine,The People`s Liberation Army No.989 Hospital,He'nan Province,Luoyang,471031 China;Department of Gastroenterology,The People`s Liberation Army No.989 Hospital,He'nan Province,Luoyang,471031 China)
Abstract:
Objective:To evaluate the efficacy of periodontal intervention on serum inflammatory cytokine levels in type 2 diabetic patients with chronic periodontitis.Methods:Databases of Pubmed,Embase,Cochrane library,CBMdisk,VIP and CNKI were searched.The meta-analysis was performed using Revman 5.3.Results:12 RCTs with 1064 cases were identified.After 3 months of periodontal intervention in test group,the levels of CRP,IL-6 and TNF-αwere significantly lower than in the control group(P<0.05).Conclusion:Periodontal intervention can decrease inflammatory cytokine levels in type 2 diabetic patients with chronic periodontitis.
Keywords:Periodontal intervention  Type 2 diabetes mellitus  Chronic periodontitis  Inflammatory cytokine  Meta-analysis
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