| 丹参活性成分对心肌缺血再灌注损伤保护作用及机制研究进展 |
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| 引用本文： | 李永鑫,高彦宇,胡晓阳,沈芳玲,李文慧,李冀. 丹参活性成分对心肌缺血再灌注损伤保护作用及机制研究进展[J]. 中医药学报, 2021, 0(4): 106-111 |
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| 作者姓名： | 李永鑫 高彦宇 胡晓阳 沈芳玲 李文慧 李冀 |
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| 作者单位： | 黑龙江中医药大学基础医学院 |
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| 基金项目： | 国家自然科学基金项目(81874426)。 |
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| 摘 要： | 丹参为现代临床治疗心血管疾病的常用中草药,其主要活性成分包括水溶性酚酸类及脂溶性二萜醌类等。近年来关于丹参活性成分防治心肌缺血再灌注损伤相关机制不断被揭示。本文查阅近年来国内外相关文献,就丹参主要活性成分抗心肌缺血再灌注损伤机制进行综述。
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| 关 键 词： | 丹参 活性成分 心肌缺血再灌注 作用机制 |
Research Progress on the Protective Effect and Mechanism of Active Components of Salvia miltiorrhiza in Treating MIRI |
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| LI Yongxin,GAO Yanyu,HU Xiaoyang,SHEN Fangling,LI Wenhui,LI Ji. Research Progress on the Protective Effect and Mechanism of Active Components of Salvia miltiorrhiza in Treating MIRI[J]. Acta Chinese Medicine and Pharmacology, 2021, 0(4): 106-111 |
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| Authors: | LI Yongxin GAO Yanyu HU Xiaoyang SHEN Fangling LI Wenhui LI Ji |
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| Affiliation: | (School of Basic Medical Sciences,Heilongjiang University of Chinese Medicine,Harbin 150040,China) |
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| Abstract: | Salvia miltiorrhiza is a commonly used Chinese herb in modern clinical treatment of cardiovascular diseases.Its main active components include water-soluble phenolic acids and lipid soluble diterpenoid quinones.The action mechanism of its active ingredients in the prevention and treatment of myocardial ischemia-reperfusion injury(MIRI)has been revealed in recent years.This study reviewed the mechanism of Salvia miltiorrhiza in treating MIRI based on related literature home and abroad. |
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| Keywords: | Salvia miltiorrhiza Active components Myocardial ischemia-reperfusion Action mechanism |
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