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妊娠期肝内胆汁淤积症孕妇肝功能变化与围生儿预后的关系
引用本文:殷艳,王冬梅,袁海琳. 妊娠期肝内胆汁淤积症孕妇肝功能变化与围生儿预后的关系[J]. 新疆医科大学学报, 2005, 28(2): 159-161
作者姓名:殷艳  王冬梅  袁海琳
作者单位:新疆医科大学第一附属医院爱婴病房,新疆,乌鲁木齐,830054
摘    要:目的:探讨妊娠期肝内胆汁淤积症(ICP)孕妇肝功能变化与围生儿预后的关系。方法:对我院1998 年~2004年5月确诊为ICP的143例孕妇临床资料进行回顾性分析。结果:血清谷丙转氨酶(ALT)>40 U/L、总胆红素(TBIL)>28μmol/L的孕妇,羊水污染及新生儿窒息发生率增加,且ALT水平越高,其发生率越高。结论:ICP孕妇ALT及TBIL水平升高者胎儿预后不佳,必须高度重视,严密监护,适时终止妊娠。

关 键 词:妊娠期肝内胆汁淤积症 肝功能 胎儿 新生儿窒息
文章编号:1009-5551(2005)02-0159-03
修稿时间:2004-08-26

Relationship between maternal hepatic function and prognosis in intrahepatic cholestasis of pregnancy
YIN Yan,WANG Dong-mei,YUAN Hai-lin. Relationship between maternal hepatic function and prognosis in intrahepatic cholestasis of pregnancy[J]. Journal of Xinjiang Medical University, 2005, 28(2): 159-161
Authors:YIN Yan  WANG Dong-mei  YUAN Hai-lin
Abstract:Objection: To investigate the relationship between hepatic function of mothers and prognosis of fetus in intraheptic cholestasis of pregnancy. Methods: Retrospective study of 143 patients with ICP. Results: The incidence of meconium passage and fetal distress were perfectly high in mothers of high serum transaminase and bilirubin. The higher of ALT level, the higher of its incidence rate. Conclusion:The faetal prognosis of mothers with high level serum transaminase and bilirubin is bad, so they must be taken great aware of and monitored closely, the pregnancy should be ended timely.
Keywords:intrahepatic cholestasis of pregnancy (ICP)  liver function  fetus  fetal distress
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