2型糖尿病患者代谢综合征和非酒精性脂肪肝的相关性

目的：探讨2型糖尿病患者代谢综合征（MS）和非酒精性脂肪肝的相关性。方法：对253例2型糖尿病患者空腹行腹部B超检测，根据有无MS．分为MS组与非MS组，比较两组非酒精性脂肪肝的患病率，应用logistic回归分析MS和非酒精性脂肪肝的相关性。结果：（1）MS组非酒精性脂肪肝患病率显著高于非MS组（27．39％vs8．33％，P〈0．001）。（2）随着MS各主要组分集簇的增加，非酒精性脂肪肝患病率也显著增加，有统计学差异。（3）单因素logistic回归分析显示，MS与非酒精性脂肪肝显著相关（OR=4．149，95％CI1．856～9．274）。结论：MS患者非酒精性脂肪肝的患病率显著升高，MS是非酒精性脂肪肝的重要危险因素。

The correlation between metabolic syndrome and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

Objective： To explore the relationship between metabolic syndrome （MS） and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. Methods： 253 patients received measurement of type B ultrasonic waves of abdomen in their empty stomachs.They were divided into MS groups and the non-MS groups according to the diagnostic criteria for MS.We compared prevalence rate of the two groups and analyzed the relationship between MS and nonalcoholic fatty liver disease with the application of logistic regression analysis. Results： （1）The prevalence of nonalcoholic fatty liver disease in MS group were significantly higher than that of non-MS group （27.39%vs8.33% ,P〈0.001）. （2） With components of the metabolic syndrome increased, the prevalence of nonalcoholic fatty liver disease a/so increased.（3） Single- factor logistic regression analysis showed tbat there was significant correlation between MS and nonalcoholic fatty liver disease （OR =4.149,95% CI 1.856-9.274）. Conclusion： The morbidity of nonalcoholic fatty liver disease in the patients suffered by MS goes up obviously.MS is the important risk factor of nonalcoholic fatty liver disease.